V. Vulnificus has a mutation in one of its metalloprotein components that hinders it from obtaining iron its transporting protein transferrin and lactoferrin. These observations have led researchers to be convinced that iron plays a crucial role in the virulence of V. Vulnificus and other microbes as well. Microbes such as Yersinia species rapidly proliferate and reproduce in body fluids that are rich in iron and macrophages