Genetic Variants Influencing Effectiveness of Exercise Training Programmes

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Introduction

  • Intended Audience: Healthcare professionals, medical students, academics
  • Author Background: All three authors have extensive medical backgrounds.
  • Writers Angle: The authors examine human predisposition towards obesity from the genetics point of view and observe how this predisposition is affected by physical training and other factors, such as diet, socioeconomic factors, education, etc.

The One-Sentence Summary

This research studies the influence of most common genetic markers that indicate a predisposition towards obesity, and their correlation with other factors, with the focus being on physical training programs.

The One-Paragraph Summary

This research is a literature review that assembles and analyses all currently available knowledge dedicated to the correlation between genetic markers and their responses to various training programs. The authors provide in-depth analysis on each of the following genes: FTO, MC4R, ACE, PPARG, LEP, LEPR, ADRB2, and ADRB3 (Leonska  Duniec, Ahmetov, & Zmijewski, 2016). The study concludes that while genetic predisposition theory is supported by a well-developed evidence base, the available literature does not take many other factors into accounts, such as daily food intake, discrepancy and volume, socio-economic factors, and education.

The Multi-Paragraph Summary

This research is a literature review performed by a small board of Polish and Russian specialists, which is dedicated to reviewing and assembling all available knowledge about the influence of predominant genetic markers, such as FTO, MC4R, ACE, PPARG, LEP, LEPR, ADRB2, and ADRB3, on modern obesity training programs.

According to the research, different genes react differently to different kinds of training exercises. For example, according to some sources, the FTO gene shows no effect on physical activity. Similar results were found for ACE and PPARG genes. At the same time, the carriers of the ADRB3 gene have demonstrated a great loss of weight after the completion of a 12-week training exercise regimen (Leonska  Duniec et al., 2016).

In conclusion, the authors state that factors outside of their control may have influenced the results of experiments analyzed in this literature review, such as daily food intake, discrepancy and volume, socio-economic factors, and education. Additional research may be necessary (Leonska  Duniec et al., 2016).

Your Reaction

The authors offer a well-rounded argument backed up by more than 80 examples of peer-reviewed literature dedicated to the subject, which adds to the articles credibility and trustworthiness. I agree with their assessments regarding genetic predisposition and its effect on aerobic exercise. I also agree with the careful assessment of the limitations of this study. The article does not appeal to emotions and operates with facts supported by the literature. It is well-suited for students, healthcare specialists, and academics to use as a base for their research. The authors did not use any graphs or tables in order to compartmentalize their data.

References

Leonska  Duniec, A., Ahmetov, I.I., & Zmijewski, P. (2016). Genetic variants influencing effectiveness of exercise training programmes. Biology of Sport, 33(3), 207-214. Web.

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