Category: the exclusion of dead cells because of insufficient nutrients from dead cells due to the toxicity of the drugs
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the toxicity of the drugs on cells in static culture is greater than cells in perfusion culture. The low toxicity observed on the activity of drugs on MTs in perfusion culture is due to three reasons. These include higher proliferation rates and the higher viability of cells in perfusion culture. On the other hand
the drug responses to paclitaxel and cisplatin in static culture and perfusion culture have significant differences. For cisplatin