Category: Penicillin

Penicillin was one of the first antibiotics discovered by A.Fleming. The accidental findings lead to treatment of worldwide spread disease as penicillin molecule inhibited the synthesis of the bacterial cell wall by mimicking the acyl-D-alanyl-D-alanine of peptide side chain and soon the new peptidoglycan (PGN) formation is stopped and bacteria cell is susceptible to osmotic…

Formation of the bacterial cell wall, during the process of cell division. When the bacterial cell is dividing, it needs to cross-link strings of polymers involving sugars and peptide chains of amino acids. In order for this to happen, it introduces an enzyme called transpeptidase. Penicillin is now known to block the action of transpeptidase…

1.0 Introduction: Bacteria are microscopic, single-celled organisms that thrive in diverse environments. They constitute a large domain of prokaryotic microorganisms and can be divided into two groups: gram-positive or gram-negative. Staphylococcus epidermidis is a gram-positive bacterium mostly found on human skin. Although most strands of S. Epidermidis are harmless, S. Epidermidis can become pathogenic and…

1.0 Introduction Penicillin G continues to remain an essential component of the medical toolkit, displaying unmatched activity against susceptible bacterial infections. To this day, it continues to be the focus of much research interest. Namely, this is due to its commercial and therapeutic importance, difficulty of cell growth, and consequence of engineering variables (Patnaik, 2001).…

History of Health Care Discovery of Penicillin Penicillin is a group of antibiotics which includes: penicillin G, penicillin V, procaine penicillin, and benzathine penicillin that attack a wide range of bacterial infections. Penicillin antibiotics is one of the first medications that is effective against many bacterial infections caused by staphylococci and streptococci. A man by…