Category: due to the high importance of disordered proteins
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IDPs and proteins with IDRs evolve faster than ordered fragments. It was also supposed that primary polypeptides were disordered and that these proteins allowed the evolution of more complex living organisms.
Thus
such as cancer and neurodegenerative diseases. These diseases appeared if certain proteins in human body started functioning in the wrong way. The rate of evolution of ordered and disordered proteins is also different. Generally